Plasma Membrane Models
نویسندگان
چکیده
منابع مشابه
Plasma Membrane
The mechanism whereby cAMP stimulates Cl flux through CFTR ion channels in secretory epithelia remains controversial. It is generally accepted that phosphorylation by cAMP-dependent protein kinase increases the open probability of the CFTR channel. A more controversial hypothesis is that cAMP triggers the translocation of CFTR from an intracellular pool to the cell surface. We have monitored me...
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The localization of plasma membrane H+-ATPase has been studied at the optical microscope level utilizing frozen and paraffin sections of Avena sativa and Pisum sativum, specific antiATPase polyclonal antibody, and second antibody coupled to alkaline phosphatase. In leaves and stems the ATPase is concentrated at the phloem, supporting the notion that it generates the driving force for phloem loa...
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Transport of [14C]tetraethylammonium (TEA), an organic cation, was studied in brush-border (BBMV) and basolateral (BLMV) membrane vesicles isolated from rabbit kidney cortex. In BBMV, the presence of an outwardly directed H+ gradient induced a marked stimulation of TEA uptake against its concentration gradient (overshoot phenomenon), whereas a valinomycin-induced inside-negative potential had n...
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Receptors are macromolecules in or on cells that mediate physiological responses upon binding specific li-gands. Over the past few years, important advances have been made in the understanding of the biology of receptors, both at a basic and at a clinical level. Receptors bind their ligands with remarkable selectiv-ity and with high affinity, permitting a given physiological response to be elic...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2018
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.11.2229